The renoprotective effect of the angiotensin-receptor blockers in patients with nephropathy

Written by Szendrei Boglárka oh., Dandei Árpád oh., Bán Erika oh., Máthé Lehel

The purpose of this study is to demonstrate the renoprotective effect of the ARBs in patients with nephropathy due to type 2 diabetes or hypertension. We administered three kinds of treatment regimens to patients with type 2 diabetes and/or high blood pressure who also exhibited microalbuminuria: the first with ARBs, the second with ACE inhibitors and the third with both. After a course of 24 weeks of treatment with ARBs, we demonstrated a significant improvement of the microalbuminuria, but the combined type of therapy was the most effective. The fall in blood pressure did not show a significant difference among patients groups. In conclusion, this pharmacologic group offers a great deal of renal protection, which shows an independent pattern to the blood pressure decreasing effect.

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